hiv-1 rt — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7212	Delavirdine mesylate	U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate)	HIV Protease , Reverse Transcriptase
	Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).		HIV Protease , Reverse Transcriptase
T81431	Pol (476-484), HIV-1 RT Epitope
	Pol (476-484), HIV-1 RT Epitope is a biologically active peptide and represents the dominant HLA A0201-restricted epitope within HIV*-1 reverse transcriptase (RT), spanning Pol residues 476-484. It has been utilized to e...
T7455	4-Chloro-2-(trifluoroacetyl)aniline hydrochloride		HIV Protease
	4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) .		HIV Protease
T2393	Efavirenz	EFV,DMP 266,Sustiva,Stocrin,L-743726	HIV Protease , Reverse Transcriptase , Autophagy
	Efavirenz (DMP 266) is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of efavirenz is as a Non-Nucleoside Reverse Transcriptase Inhibitor, and Cytochrome P...		HIV Protease , Reverse Transcriptase , Autophagy
T3172	Trovirdine	LY300046	HIV Protease
	Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.		HIV Protease
T12715	Reverse transcriptase-IN-1		HIV Protease
	Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7 nM.		HIV Protease
T61311	HIV-1 inhibitor-30
	HIV-1 inhibitor-30 (compound 10i) is a potent inhibitor of HIV-1, specifically targeting the RT DNA polymerase enzyme. It exhibits strong antiretroviral activity, with an EC 50 value of 40 nM and an IC 50 value of 80 nM....
T70586	S 2720
	S 2720 is a human immunodeficiency virus type 1 (HIV-1)-specific reverse transcriptase (RT) inhibitor quinoxaline.
T72461	EFdA-TP tetrasodium		Reverse Transcriptase
	EFdA-TP tetrasodium, a potent nucleoside reverse transcriptase (RT) inhibitor, effectively halts RT-catalyzed DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT). It employs multiple mechanis...		Reverse Transcriptase
T63963	HIV-1 inhibitor-14
	HIV-1 inhibitor-14 is a potent, broad-spectrum inhibitor of HIV-1 non-nucleoside reverse transcriptase (RT) (IC50=0.14 μM for HIV-1 RT). HIV-1 inhibitor-14 inhibits both wild-type and drug-resistant HIV-1 strains (EC50: ...
T37910	Tenofovir diphosphate triethylamine
	Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive inhibitor of DNA polymerases for dATP, functioning as a substrate for HIV type 1 reverse transcriptase (HIV-1 RT)[1].
T63890	HIV-1 inhibitor-22
	HIV-1 inhibitor-22 is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (RT) (HIV-1 RT: IC50=3.63 μM). M and also showed low cytotoxicity with a CC50 > 227 μM.
T63813	HIV-1 inhibitor-39
	HIV-1 inhibitor-39 is a potent inhibitor of HIV-1 (EC50>112.88 μM). HIV-1 inhibitor-39 has anti-RT (HIV-1 reverse transcriptase) effect (IC50: 15.75 μM). HIV-1 inhibitor-39 exhibits cytotoxicity against MT-4 cells (CC50:...
T62287	HIV-1 inhibitor-42
	HIV-1 inhibitor-42 (compound 5b) is a potent inhibitor of HIV-1 (IC50: 0.06 μM). HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase (IC50: 0.518 μM) and DNA-dependent DNA polymerase (IC50. 0.072 μM).
T27768	L-696229	L696,229,L-696,229,L 696229,L696229,L 696,229
	L-696229 is a specific inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). L-696229 inhibited RT activity in a mutually exclusive manner with respect to either phosphonoformate or azidoth...
T63113	HIV-1 inhibitor-21
	HIV-1 inhibitor-21 (compound 9b) is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (RT) and acts on HIV-1 RT (IC50: 0.55 μM). HIV-1 inhibitor-21 inhibits both wild-type HIV-1 (EC50: 12.7 nM) and mutant ...
T35649	EFdA-TP tetraammonium
	EFdA-TP tetraammonium is an influential nucleoside reverse transcriptase (RT) inhibitor that effectively prevents RT-mediated DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT). Additionally...
T24839	Stampidine	HI-113,HI 113,HI113
	Stampidine can prevent the sexual transmission of HIV-1. It exhibited remarkable subnanomolar to low nanomolar in vitro antiretroviral potency against nucleoside reverse transcriptase inhibitor-resistant primary clinical...
T37909	Tenofovir diphosphate
	Tenofovir diphosphate (TFV-DP) is a competitive inhibitor of DNA polymerases, specifically targeting dATP, and it serves as a substrate for the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1)[1]...
T79324	HIV-1 inhibitor-59
	HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM. Additionally, it demonstrates moderate inhibitory activity against the rev...